Purpose: This study was conducted to find out the effects od Sahyangsohapwon on learning and memory of rats.
Method: In the experiment, rats were divided two groups. One was control group which was adminstered Sahyangsohapwon and the other was sample group administered placebo. Numbers of each group were 13 rats. 8-arm radial maze task was used in it, and working memory test and retention(reference memory) test were done.
Before the beginning of the test, the rats were deprived of water for 24hrs.
In the frist test, each of eight arm was baited with water and a rat was permitted to remain on the maze until all eight arms were entered. A working memory error was defined as revisit of any previously entered arm. When a rat made an error not exceeding one time in consecutive 3 days-performance, it was regarded as learning criteria and the test was ended. The reference memory was evaluated with total days which it took rats to pass the learning crtirtia.
The second test was performed after 24 hours when the first test was over. When a rat entered 4 arms, the entrance of arm was cut off during 30 seconds.
Here the number if errors which was produced during a rat find remaining 4 tracks was regarded as the index of memory.
This experiment compared the number of error at the control group with that of the sample group.
Result: 1. In the first test, it was shown that the sample group took 7.69±1.11 days and the control group 9.31±1.97 days to pass the learning criteria.
There was statistically significant reference mernory development at the sample group.
2. In the second test, the frequency of errors made by the two groups were 0.92±1.32 times for the control group and 1.23±1.59 times for the Sahyangsohapwon group. There was no difference between the groups in frequency of errors.
Conclusion: It is suggested that Sahyangsohapwon has effects on the improvement of learning and memory.
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